The Holy Quran is an eternal and universal heavenly book that has been sent by God for the happiness and guidance of mankind through the last divine messenger, and it will be the guide of mankind until the end of the material world and the establishment of the Day of Judgment. This eternal miracle has the characteristic of being universal and universal and will not become obsolete or invalidated with the passage of time. The purpose of the present study is to examine the reasons for the eternity and universality of the Holy Quran from the perspective of Ayatollah Javadi Amoli, as a great jurist and renowned commentator of the Holy Quran. The present text, considering his opinions and views, from an intra-religious perspective and with an analytical approach, has tried to answer the question: what reasons does he examine for the universality of the Holy Quran? Considering the above purpose and question, he has studied the subject using documentary research method and has reached the following conclusions: from his perspective, in addition to many verses of the Quran that indicate its universality, features such as naturalism and the natural language of the Quran, valuing knowledge and reason, justice, divine dignity of man, the universal mission of the Prophet (PBUH), the comprehensive divine and human values, the infallibility and non-distortion of the Quran indicate the immortality and universality of this book of guidance.